Hidden pocket reveals new way to target prostate cancer's 'undruggable' ERG protein
In the United States, prostate cancer is a leading cause of cancer-related disease and death in men. About half of prostate cancer cases in patients of European ancestry have a gene rearrangement in which the genes TMPRSS2 and ERG are fused together. This causes the ERG protein to be turned on, incr
<p>In the United States, prostate cancer is a leading cause of cancer-related disease and death in men. About half of prostate cancer cases in patients of European ancestry have a gene rearrangement in which the genes TMPRSS2 and ERG are fused together. This causes the ERG protein to be turned on, incr</p>