How mutation disrupts cell development, driving region-specific brain tumors
Scientists at St. Jude Children's Research Hospital have shown that specific brain cells respond differently to H3.3 K27M, a mutation in the histone H3.3 protein that drives many cases of diffuse midline glioma (DMG), depending on the cells' location in the developing brain. These findings help expl
<p>Scientists at St. Jude Children's Research Hospital have shown that specific brain cells respond differently to H3.3 K27M, a mutation in the histone H3.3 protein that drives many cases of diffuse midline glioma (DMG), depending on the cells' location in the developing brain. These findings help expl</p>