Oyster surfaces with $60m and a tau degrader that travels light
Formerly Kesmalea, the London company says its degraders cross the blood-brain barrier in pieces, then self-assemble on the other side. Targeted protein degradation has a size problem. The bifunctional molecules that dominate the field – two warheads joined by a linker, one gripping the disease prot
<p>Formerly Kesmalea, the London company says its degraders cross the blood-brain barrier in pieces, then self-assemble on the other side. Targeted protein degradation has a size problem. The bifunctional molecules that dominate the field – two warheads joined by a linker, one gripping the disease prot</p>