Protein guides cytoneme 'highway' formation to support developmental signaling
Cytonemes are tendril-like appendages that developing cells use to communicate across large distances. Their cargo—including the key signaling protein Sonic Hedgehog (SHH)—is highly specific, but the mechanisms underlying this specificity were unclear.
<p>Cytonemes are tendril-like appendages that developing cells use to communicate across large distances. Their cargo—including the key signaling protein Sonic Hedgehog (SHH)—is highly specific, but the mechanisms underlying this specificity were unclear.</p>